Headshot of Scott Wood

Scott T. Wood, Ph.D.

Director, Portland Laboratory for Biotechnology and Health Sciences
Office of Research and Scholarship
Associate Professor
Department of Biomedical Sciences

Location

Pharmacy 320
Portland Campus for the Health Sciences
Eligible for Student Opportunities

The Wood lab focuses on using tissue engineering strategies to better understand, quantify, and predict the behavior of cells in response to physical stimuli. They focus on investigating the homeostatic role of the chondrocyte cytoskeleton and its intersection with integrin signaling pathways and on the development of a Microphysiological Articular Joint In a Chip (MAJIC) to model the multi-tissue nature of human articular joints in a microfluidic system that can be used as a drug screening tool.

Credentials

Education

Ph.D. in Bioengineering
Clemson University
2011
M.S. in Bioengineering
Clemson University
2010
B.S. in Mechanical Engineering
Texas Tech University
2005
Certificate in Technology Entrepreneurship
Clemson University
2011

Expertise

  • 3D printing
  • Applied mathematical analysis
  • Atomic force microscopy
  • Biomaterials
  • Biomechanics
  • Biomedical research
  • Cell culture
  • Data analysis
  • Fluorescence microscopy
  • Image analysis
  • Immunocytochemistry
  • Knee osteoarthritis

Post-Doctoral Training

Postdoctoral Research Associate, Richard Loeser, M.D. Lab, Thurston Arthritis Research Center, University of North Carolina-Chapel Hill (Chapel Hill, NC) & Department of Internal Medicine-Section on Molecular Medicine, Wake Forest School of Medicine (Winston-Salem, NC), 2012-2016

Research

Selected publications

  • Nix Z*, Kota D*, Ratnayake I*, Wang C, Smith S, Wood ST. Spectral characterization of cell surface motion for mechanistic investigations of cellular mechanobiology. Progress in Biophysics and Molecular Biology. 2022. 176:3-15. doi: .
  • Saraswat R*, Ratnayake I*, Perez EC†, Schutz, WM†, Zhu Z, Ahrenkiel SP, Wood ST. A micropatterned biphasic nanocomposite platform for maintaining chondrocyte morphology. ACS Applied Materials and Interfaces. 2020. 12(13):14814-14824. doi:. 
  • Collins JA, Wood ST, Bolduc JA, Nurmalasari NPD*, Chubinskaya S, Poole LB, Furdui CM, Nelson KJ, Loeser RF. Differential Peroxiredoxin Hyperoxidation Regulates MAP Kinase Signaling in Human Articular Chondrocytes. Free Radical Biology and Medicine: 2019. 134:139-152. doi:. 
  • Nelson KJ, Bolduc J, Wu H, Collins JA, Burke EA, Reisz JA, Klomsiri C, Wood ST, Yammani RR, Poole LB, Furdui CM, Loeser RF. H2O2 oxidation of cysteine residues in c-Jun N-terminal kinase 2 (JNK2) contributes to redox regulation in human articular chondrocytes. The Journal of Biological Chemistry: 2018. 19;293(42):16376-16389. doi:.